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Figure 1: Models of cyclization reaction of CGTase on amylose. A is a conventional model for the action of CGTase. B is a proposed model. Solid lines and circles indicate α-1, 4-glucan chains, where the relative length represents their relative DP. R, glucosyl residue with reducing end; Δ, α-1, 4 linkage attacked by CGTase; CD, α-, β-, γ-CD. Reprinted from [16]. Cyclodextrins are not the major cyclic α-1, 4-glucans produced by the initial action of cyclodextrin glucanotransferase on amylose, 25 pp 15729-15733, Reprinted with permission. Copyright (1997) The American Society for Biochemistry and Molecular Biology, Inc. |