Pharmacokinetic parameters Test product Oranor® coated tablet400 mg
n= 26
Reference product Noroxin® Tablets 400 mg
n= 26
t-student test p value
Cmáx dn
(ng/mL/mg/kg)
0.0533 ± 0.0218
40.79
0.0541 ± 0.0197
36.33
p= 0.8947
AUC0-t dn
(ng*h/mL/mg/kg)
0.2301 ± 0.0866
37.65
0.2477 ± 0.0859
34.68
p= 0.4659
AUC0-∞dn
(ng+h/mL/mg/kg)
0.2457 ± 0.0905
36.84
0.2643 ± 0.0903
34.17
p= 0.4613
dn: dose normalized mg/kg
Promedio ± SD
C. V. (%)
Table 2: Norfloxacin pharmacokinetic dose normalized parameters (mg/kg).