| PK Parametre |
Diabetmin 250mg tablet (Test) |
Sunward Metformin 250mg tablet (Reference) |
| AUC0-t (hr.ng/ml) |
4680.7 ± 1163.23 |
4882.1 ± 1157.44 |
| AUC0-∞ (hr.ng/ml) |
4862.5 ± 1153.84 |
5043.1 ± 1187.02 |
| Cmax (ng/ml) |
727.5 ± 167.89 |
772.6 ± 171.27 |
| Tmax (hr) |
2.98 ± 0.859 |
3.13 ± 0.828 |
| T1/2 (hr) |
3.70 ± 1.629 |
3.65 ± 1.203 |
| Ke (hr-1) |
0.21 ± 0.066 |
0.21 ± 0.066 |
Legend: sd, standard deviation; AUC0-t, area under the plasma-concentration curve from dosing to last quantifiable time point; AUC0-∞, area under the plasma-concentration curve from dosing to infinity; Cmax, peak plasma concentration; Tmax, time to reach peak plasma concentration; Ke, elimination rate constant |
