Journal of Carcinogenesis & Mutagenesis

Onofri Azzurra

Publications

• Research Article
  Thymic Malignancies in the Targeted Therapies Era
  Author(s): Berardi Rossana, De Lisa Mariagrazia, Pagliaretta Silvia, Paolucci Vittorio, Morgese Francesca, Savini Agnese, Caramanti Miriam, Ballatore Zelmira, Onofri Azzurra and Cascinu StefanoBerardi Rossana, De Lisa Mariagrazia, Pagliaretta Silvia, Paolucci Vittorio, Morgese Francesca, Savini Agnese, Caramanti Miriam, Ballatore Zelmira, Onofri Azzurra and Cascinu Stefano
  
  Objective: In the last years, significant efforts have been made in order to improve the knowledge of molecular biology of thymic malignancies. The purpose of this manuscript is to review the recent advances in the treatment of refractory, recurrent thymomas and thymic carcinomas, focusing on molecular targeted therapy and on the previous or actually ongoing clinical trials and genomic analysis. Methods: Available literature on the topic of thymic malignancies was extensively reviewed, using the MEDLINE, CancerLit and ClinicalTrial.gov databases. We searched for targeted therapies studies between restricting our search to English-language publications, including the following search terms: “targeted therapy, octreotide, molecular alterations and pathways” in association with thymoma, thymic carcinoma and thymic neoplasms/ malignancies. Results: Recent thymic malignancies&r.. View More»
  DOI: 10.4172/2157-2518.S8-008

  Abstract PDF