Dentistry

Prapan Suppakpatana

Publications

• Research Article
  Morinda citrifolia Leaf Enhances In Vitro Osteogenic Differentiation and Matrix Mineralization by Human Periodontal Ligament Cells
  Author(s): Kanitsak Boonanantanasarn, Kajohnkiart Janebodin, Prapan Suppakpatana, Tawepong Arayapisit, Panjit Chunhabundit, Jit-Aree Rodsutthi, Orapin Termvidchakorn and Wanida SripairojthikoonKanitsak Boonanantanasarn, Kajohnkiart Janebodin, Prapan Suppakpatana, Tawepong Arayapisit, Panjit Chunhabundit, Jit-Aree Rodsutthi, Orapin Termvidchakorn and Wanida Sripairojthikoon
  
  Morinda citrifolia L. (noni) has been reported to have a variety of potentially therapeutic effects such as antibacterial, antiviral, antifungal, antitumor, antihelmin, analgesic, hypotensive and anti-inflammatory, as well as immune enhancing properties. In this study, we aimed to investigate a potential effect of Morinda citrifolia leaf aqueous extract to induce osteogenic differentiation and matrix mineralization of human periodontal ligament (hPDL) cells in vitro. The optimal biocompatible dose of noni leaf aqueous extract was determined by a cell proliferation assay. The hPDL cells were cultured in growth medium alone, or medium supplemented with noni leaf aqueous extract, or β-glycerophosphate and ascorbic acid. The early osteogenic differentiation marker, alkaline phosphatase activity, was assayed using a biochemical analys.. View More»
  DOI: 10.4172/2161-1122.1000130

  Abstract PDF