A group of scientists from Indian Institute of Science, Bangalore, India have developed a shock wave-based drug delivery system that could be used to administer insulin in diabetic patients and reduce the need for painful injections. A similar strategy could also increase the efficacy of antibiotic treatment to diabetic wounds. In a parallel experiment, the team demonstrated that ciprofloxacin released from the microparticles upon exposure to micro-shock waves could rescue diabetic mice from a superficial Staphylococcus aureus skin infection. This was not the case when micro-shock waves were not used and is thought to be because they promote bacterial biofilm disruption, wound healing and angiogenesis.
By Megan Tyler