Hematopoiesis term includes formation of blood cellular components. These blood cellular components are derived from Hematopoietic stem cells. These cells are not limited to the bone marrow compartment and function beyond their role in hematopoiesis. Hematopoietic stem cells (HSC) maintain and replenish all blood cell types in the bone marrow and respond to changing needs for blood cells in peripheral tissues. These cells give rise to all the other blood cells and are derived from mesoderm. In a healthy adult individual, roughly 1011â1012 new body-fluid cells are made every day in alignment to sustain steady state levels in the peripheral circulation. Hematopoietic stem cell resides in specialized microenvironments (niches) in the bone marrow. Journal of blood Disorders & Transfusion involves recent research that lightened on novel functions of hematopoietic stem and progenitor cells.
Last date updated on April, 2021