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Journal of Dental Science and Medicine | ISSN: 2572-4835 | Volume 3
27
TH
AMERICAN DENTAL CONGRESS
December 07-08, 2018 | Chicago, USA
Silver nanoparticles: An alternative approach to treat dental caries
T
he use of silver in oral care is known for centuries and have recently renewed, since nanotechnology evolved and the
outstanding antimicrobial properties of nanostructured silver-based formulations have been demonstrated against many
different microorganisms. Several promising new technologies are currently under development and our group have recently
demonstrated that formulations based on silver nanoparticles can be effective for caries arrestment without staining teeth,
which make them a very attractive alternative to the “milling and filling” approach. Untreated dental caries in children remains
a public health challenge in developing countries that affects future dental health, growth and cognitive development. The
antimicrobial and cytotoxic activity of formulations containing silver nanoparticles (AgNP) against
Streptococcus mutans
were
evaluated and compared to chlorhexidine and silver diamine fluoride (SDF). AgNPs is as effective as SDF in much lower doses
and are non-cytotoxic. The clinical trials were carried out in children (6 - 9 years old) and the formulations were applied to
deciduous teeth.
Biography
Andre Galembeck has a background in Materials Chemistry (UNICAMP, 1998) and is, currently, the Director of the Centro de Tecnologias Estratégicas do Nordeste
(CETENE), a National Research Institute, in Brazil. He has been formerly a member of the National Advisory Committee on Nanotechnology, published more
than 60 peer-reviewed articles in international journals and filed 8 patents. The research activities are related with nanostructured materials and polymer-based
nanocomposites, mainly devoted for health applications.
andre@ufpe.brAndre Galembeck
Universidade Federal de Pernambuco, Brazil
Andre Galembeck, J Dent Sci Med 2018, Volume 3
DOI: 10.4172/2572-4835-C1-004