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Dementia 2016
September 29-October 01, 2016
Volume 6 Issue 5(Suppl) J Alzheimers Dis Parkinsonism 2016
ISSN:2161-0460 JADP, an open access journal
conferenceseries .com
September 29-October 01, 2016 London, UK
5th International Conference on
Alzheimer’s Disease & Dementia
Anita Saltmarche et al., J Alzheimers Dis Parkinsonism 2016, 6:5(Suppl)
Impact of physical and mental insults on dementia: Clinical observations following a transcranial-
intranasal photobiomodulation therapy study
Anita Saltmarche1, Margaret A Naeser, LicA2, Kai Fai Ho3, Michael R Hamblin4,5,6 and Lew Lim ND7
1Saltmarche Health & Associates Inc., Canada
2Boston University School of Medicine, USA
3STAT-TU Inc., Canada
4Massachusetts General Hospital, USA
5Harvard Medical School, USA
6Harvard-MIT Division of Health Sciences and Technology, USA
7Vielight Inc., Canada
Observations reported here range from 1 week to 1 year following a randomized, single-blind placebo-controlled pilot
study to assess the effect of near infrared transcranial and intranasal photobiomodulation therapy (PBMT) on cognition
in 19 participants over 12 weeks with a 4-week no-treatment follow-up. Randomization included 13 into active and 6 into sham
treatments. Participants were assessed with MMSE and ADAS-cog scales. Participants with moderate to severe impairment
(MMSE baseline of 5-24) who received active treatment showed significant improvements on each test (p<0.03) after 12 weeks.
They also reported better sleep, fewer angry outbursts, decreased anxiety, and less wandering. Declines were noted during
the final 4 weeks without treatments. No related adverse events were reported. After the 16-week study all participants were
given active PBMT devices for home treatment. We continued to monitor the participants every 6 to 8 weeks, and observed
that those with physical and mental insults suffered negative impact on their cognition, whereas those who did not, retained
or continued with improvements. Physical insults included foot ulcer, chronic pain, influenza, major surgery, and pneumonia.
Mental insults included grief from a family loss, property fire, work-related and emotional stress. In conclusion, we observed
that improvements from PBMT were maintained when those with dementia did not experience physical trauma and mental
stress. Although these observations relate to a PBMT study, they suggest that the effects of additional diseases, accidents,
and mental/emotional stress factors need to be incorporated into data analysis that could develop into long-term treatment
protocols for dementia.
Biography
Anita Saltmarche completed her Masters of Health Sciences from McMaster Univeristy, Hamilton, ON, Canada. She was a geriatric clinical nurse specialists for
over a decade at Sunnybrook Health Science in Toronto as well as other leadership positions across the healthcare system. Anita manitains a clinical practice and
provides research and other consulting services to a broad group of clients ranging from the Ontario Ministry of Health & Long Term Care to a number of private
sector companies and non-profit health organizations. As principal and co-investigator on peer-reviewed research projects, she has published numerous papers
in well respected journals.