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Volume 09

Otolaryngology: Open Access

ISSN: 2161-119X

ENT 2019

Craniofacial Surgery 2019

August 15-17, 2019

JOINT EVENT

conferenceseries

.com

August 15-17, 2019 Rome, Italy

&

3

rd

International Conference on

Craniofacial Surgery

4

th

European Otolaryngology-ENT Surgery Conference

Wallach Leemor et al., Otolaryngol (Sunnyvale) 2019, Volume 09

Mixed type tumor Histiocytic Sarcoma & Langerhans Cell Sarcoma

Wallach Leemor

1

, El Khatib Nidal

2

, Szvalb Sergio MD

2

and

Merchavy Shlomo MD

1

Department of Otolaryngology and Head & Neck Surgery, Ziv Medical Center, Israel

Department of pathology, ZIV Medical Center, Israel

We present a case of a 70 Year-old man with night sweats, weight loss, bilateral leg pain and neuralgia with a single

physical examination finding of bilateral enlarged cervical lymph nodes. He was diagnosed with a rare type of

Langerhans Cell Sarcoma (LCS) mixed with Histiocytic Sarcoma (HS). Both malignancies are hard to diagnose

because they are rare and have non-specific symptoms. Furthermore, HS has similar features as Non-Hodgkin’s

lymphoma and other B-cell Lymphomas. The diagnosis in this case was made by an open biopsy from the left neck,

level IV, which revealed a 19mm hard lymph node without necrosis or adhesions. The pathology showed paracortical

and interfollicular large cell neoplasm, with intermediate/divergent phenotype between HS (Lysozyme+/CD68-

KP1+) and LCS (CD1a+/Langerin+). PET-CT showed a disseminated disease; therefore, the patient was not a

candidate for surgery. In conclusion, although this diagnosis is extremely rare, we should always include it in the

differential diagnosis process of a suspicious cervical lump or mass..

Biography

Leemor Wallach is an intern in Ziv Medical Center. She received her MD from Tel -Aviv University and

B.Sc.

in Animal Science from the Hebrew University. She

graduated with honors. Leemor was an Army medic, worked as a vet’s assistant in a veterinary hospital, a doctor’s assistant in the ER and managed a surgeon’s

clinic. She intends on pursuing a career as an otolaryngologist.

leemor.wallach@mail.huji.ac.il