

Page 75
Volume 09
Otolaryngology: Open Access
ISSN: 2161-119X
ENT 2019
Craniofacial Surgery 2019
August 15-17, 2019
JOINT EVENT
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August 15-17, 2019 Rome, Italy
&
3
rd
International Conference on
Craniofacial Surgery
4
th
European Otolaryngology-ENT Surgery Conference
Wallach Leemor et al., Otolaryngol (Sunnyvale) 2019, Volume 09
Mixed type tumor Histiocytic Sarcoma & Langerhans Cell Sarcoma
Wallach Leemor
1
, El Khatib Nidal
2
, Szvalb Sergio MD
2
and
Merchavy Shlomo MD
1
Department of Otolaryngology and Head & Neck Surgery, Ziv Medical Center, Israel
Department of pathology, ZIV Medical Center, Israel
We present a case of a 70 Year-old man with night sweats, weight loss, bilateral leg pain and neuralgia with a single
physical examination finding of bilateral enlarged cervical lymph nodes. He was diagnosed with a rare type of
Langerhans Cell Sarcoma (LCS) mixed with Histiocytic Sarcoma (HS). Both malignancies are hard to diagnose
because they are rare and have non-specific symptoms. Furthermore, HS has similar features as Non-Hodgkin’s
lymphoma and other B-cell Lymphomas. The diagnosis in this case was made by an open biopsy from the left neck,
level IV, which revealed a 19mm hard lymph node without necrosis or adhesions. The pathology showed paracortical
and interfollicular large cell neoplasm, with intermediate/divergent phenotype between HS (Lysozyme+/CD68-
KP1+) and LCS (CD1a+/Langerin+). PET-CT showed a disseminated disease; therefore, the patient was not a
candidate for surgery. In conclusion, although this diagnosis is extremely rare, we should always include it in the
differential diagnosis process of a suspicious cervical lump or mass..
Biography
Leemor Wallach is an intern in Ziv Medical Center. She received her MD from Tel -Aviv University and
B.Sc.in Animal Science from the Hebrew University. She
graduated with honors. Leemor was an Army medic, worked as a vet’s assistant in a veterinary hospital, a doctor’s assistant in the ER and managed a surgeon’s
clinic. She intends on pursuing a career as an otolaryngologist.
leemor.wallach@mail.huji.ac.il