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conferenceseries
.com
Volume 8, Issue 2 (Suppl)
J Blood Disord Transfus
ISSN: 2155-9864 JBDT, an open access journal
Hematologists 2017
May 08-09, 2017
7
th
World Hematologists Congress
May 08-09, 2017 Barcelona, Spain
Kamran Mansouri et al., J Blood Disord Transfus 2017, 8:2(Suppl)
http://dx.doi.org/10.4172/2155-9864-C1-023Warfarin dosing in a patient with CYP2C9*1*2 and VKORC1-1639 AA genotypes
Kamran Mansouri
and
Zohreh Hoseinkhani
Kermanshah University of Medical Sciences, Iran
G
enetic factor broadly influence the required doses of warfarin. Genetic factors including the presence of
CYP2C9
and
VKORC1-1639 G>A
genes have a significant effect on the due doses of warfarin in individuals. In the present study, a patient
was reported to have a high sensitivity to warfarin dosage. Thereby, he required lower dose of warfarin to get to the target INR.
VKORC1-1639 AA, CYP2C9*1*2 genotypes were revealed to exist through patient’s genetic testing.
Biography
Kamran Mansouri completed his PhD at Tehran University of Medical Sciences, Iran. He is the Head of Department of Molecular Medicine at Kermanshah
University of Medical Sciences, Iran. He has published more than 50 papers in reputed journals.
kamranmansouri@gmail.com