influenza-2016_posters-accepted-abstracts

16 / 25

Volume 4, Issue 6(Suppl) J Infect Dis Ther
ISSN: 2332-0877 JIDT, an open access journal
Page 64
Influenza 2016
September 12-13, 2016
conferenceseries.com
Influenza
September 12-13, 2016 Berlin, Germany
2nd International Conference on
J Infect Dis Ther 2016, 4:6(Suppl)
Occurrence and spread of influenza A(H1N1)pdm09 virus infection in Norwegian pig herds based on
active sero surveillance from 2010 to 2014
Chiek Jwee Er
Norwegian Veterinary Institute, Norway
The incursion of influenza A(H1N1)pdm09 virus was detected by Norway’s active sero surveillance of its pig population in 2009.
Since then, surveillance data from 2010 to 2014 revealed that 54% of 5643 herd tests involving 1567 pig herds and 28% of 23036
blood samples screened positive for antibodies against influenza A virus. Positive herds were confirmed to have influenza A(H1N1)
pdm09 virus infection by hemagglutination inhibition test. In 50% of positive herd tests, ≥60% of the sampled pigs in each herd had
antibodies against influenza A(H1N1)pdm09 virus. This within-herd animal seroprevalence did not vary for type of production, herd
size or year of test. The overall running mean of national herd seroprevalence and annual herd incidence risks fluctuated narrowly
around the means of 45% and 32%, respectively, with the highest levels recorded in the three densest pig-producing counties. The
probability of a herd being seropositive varied in the five production classes, which were sow pools, multiplier herds, conventional
sow herds, nucleus herds and fattening herds in descending order of likelihood. Large herds were more likely to be seropositive.
Seropositive herds were highly likely to be seropositive the following year. The study shows that influenza A(H1N1)pdm09 virus is
established in the Norwegian pig population with recurrent and new herd infections every year with the national herd seroprevalence
in 2014 hovering at around 43% (95% confidence interval (40-46%).
Burden of acute lower respiratory tract infection caused by influenza virus among children in Egypt
Jehan El Kholy
Cairo University Hospital, Egypt
Background: Influenza virus is one of the most important causes of acute lower respiratory tract infections (ALRTI) in children. We
aimed to assess the burden of influenza among hospitalized children less than 5 years in Egypt.
Methods: We enrolled 3075 patients, of which 77.8% were children less than 5 years old diagnosed with ALRTI admitted to Cairo
University Hospitals during five-year period from 2010 to 2014. Nasopharyngeal aspirates were obtained from the patients and tested
for influenza among 16 respiratory viruses by mutliplex PCR.
Results: Patients had a mean age of 4 months, 53.4% were males. Average hospitalization duration was 5 days, 35% were positive
for one or more virus. Influenza A and influenza B were detected in 6.2% and 3.2% of children respectively. All influenza patients
presented with cough and fever. More than 80% had tachypnea and nasal flare. Complications were associated with chronic lung
and heart conditions. The most common complications were ARDS (81.8%), requiring ICU admission (12%) and death in 8.2%;
though seasonal distribution was not consistent, yet 80% of influenza cases occurred in winter and early spring seasons (p<0.001).
Nosocomial transmission occurred in 2 outbreaks in a Surgical Pediatric Intensive care units, affecting 7 children.
Conclusion: Influenza is an important etiology of ALRTI in children below 5 years of age. As it is more prevalent in winter and tends
to cause severe infection in high risk group, vaccination, rapid diagnosis and early start of antiviral therapy are essential.