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Page 39
Volume 10
Journal of Neurology & Neurophysiology
ISSN: 2155-9562
Neurology Congress 2019
Vascular Dementia Congress 2019
July 22-24, 2019
JOINT EVENT
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July 22-24, 2019 London, UK
&
12
th
International Conference on
Vascular Dementia
32
nd
European Neurology Congress
Incidence of stroke among diabetic nephropathypatients: Ameta-analysis
Abdulrahman O. Alharbi
1
, Sultan Al Dalbhi
2
and
Norah A .Alharbi
3
1
Majmaah University, Saudi Arabia
2
Prince Sultan Military Medical City, Saudi Arabia
3
Qassim University, Saudi Arabia
Background andObjectives:
The association of micro vascular complications (diabetic nephropathy) with the stroke
is limited because it will require huge sample size of diabetic population with nephropathy and long follow-up period
to see the association or development incidence of stroke among these patients. So, we conducted out this meta-
analysis of the existing studies to find out the incidence/ risk of stroke among diabetic nephropathy patients and and,
explore the association between stroke and proteinuria in a diabetic nephropathy population and to describe Does
Degree of Proteinuria a Clinical Matter!! ?
Methods & Materials:
We searched the existing databases from the year 1995 to August 2018 by using the MeSH terms. All
cohorts, cross sectional studies were searched for, fulfilling the inclusion criteria and as per operational definitions. The quality
assessment criterion for quality of studies was already predefined.
Study Result:
Seven studies were found to be eligible for inclusion in the meta- analysis. The hazards or risk of stroke
development among diabetic patients was 3.25 times higher in patients with nephropathy as compared to patients without
nephropathy.
The pooled hazards ratio of 1.46 (95% CI=0.81-2.60) and of 1.65 (95% CI=0.53-5.11) among diabetic patients with micro
albuminuria and macro albuminuria respectively.
Abdulrahman O. Alharbi et al., J Neurol Neurophysiol 2019, Volume 10
Figure1: Forest plot- Hazard ratio of stroke among
diabetic patients with and without nephropathy
Figure2: Hazard ratio of stroke among diabetic
patients with and without Micro albuminuria
Figure3: Hazard ratio of stroke among diabetic
patients with and without Macro albuminuria