oncologists-2018-posters-abstracts

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Volume 10

Journal of Cancer Science & Therapy

Oncologists 2018

May 24-25, 2018

May 24-25, 2018 Osaka, Japan

Global Annual Oncologists Meeting

J Cancer Sci Ther 2018, Volume 10

DOI: 10.4172/1948-5956-C3-130

Fever gone malignant: A case report of squamous cell carcinoma of the renal pelvis initially presenting

as renal abscess

Christer Mari F Taclobos, Jeanette Umali and Gregorio Galve

Corazon Locsin Montelibano Memorial Regional Hospital, Philippines

he fact that the urothelium normally does not have squamous cells renders the pathogenesis of squamous cell carcinoma of

the renal pelvis

report a 69 year oldmale who initially presentedwith persistent fever evenwith antimicrobial

therapy. Patient is known to have nephrolithiasis since three years prior to admission and would experience occasional right

flank pain, not compliant to medications prescribed and was lost to follow up. Patient experienced on and off undocumented

fever for three weeks. Consult was done wherein ultrasound and computed tomography with contrast of the whole abdomen

were requested which pointed to a non-obstructing nephrolithiasis associated with an intra-renal abscess communicating to

an abscess of the right hepatic lobe. Nephrectomy was advised however patient was initially undecided thus nephrostomy

was done. There was persistence of fever with note of anorexia, abdominal enlargement and generalized body weakness thus

patient was readmitted in this institution for further medical and surgical management. Patient had slightly pale conjunctiva.

Abdominal examination revealed a nephrostomy tube inserted in the right kidney. Bowel sounds are normoactive with direct

tenderness at the right upper quadrant area. A smooth, tender, non-erythematous mass is palpated at the right upper quadrant.

There is note of right costovertebral tenderness. Patient was admitted as a case of: (1) Sepsis secondary to right renal abscess

and right hepatic lobe abscess and (2) right nephrolithiasis. Patient was immediately referred to the department of general

surgery for evaluation and co-management due to intractable leukocytosis associated with persistent fever. Notable were

persistent leukocytosis, hypercalcemia and thrombocytosis on laboratory tests. Nephrectomy was done and histopathology

report showed squamous cell carcinoma of the right kidney. Squamous renal cell carcinoma is a rare neoplasm which is always

associated with long standing renal stone and is always intensive at the time of diagnosis. Aside from renal calculi, infections

such as chronic UTI, renal TB, schistosomiasis, vitamin A deficiency, percutaneous nephrostomy and immunosuppression can

cause this entity but the main risk factor almost constant in all reported cases of squamous cell carcinoma of the renal pelvis is

a history of long standing nephrolithiasis.