8 / 27
Page 48
Notes:
conferenceseries
.com
Pain Medicine 2017
October 19-20, 2017
Volume 6, Issue 6 (Suppl)
J Pain Relief, an open access journal
ISSN: 2167-0846
October 19-20, 2017 San Francisco, USA
4
th
International Conference on
Pain Medicine
Botulinum toxin treatment using ultrasound for pain of open jaw dystonia in progressive supranuclear palsy
Jin Seok Seo
Veterans Health Service Medical Center, Korea
Objective:
Oromandibular dystonia (OMD) is an infrequent condition in progressive supranuclear palsy(PSP), which may results
in dysfunctional movements of facial, tongue muscles, mandible and temporomandibular joint. Regards of treatments, medical
treatment usually showed a little effect on dystonia, botulinum toxin injection has been focused on an alternative treatment for OMD.
In this case, we aim to report the treatment of jaw opening dystonia with botulinum toxin A in PSP using ultrasonography
Methods:
A 64-year-old man presented with tonic, extended dystonia of axial and OMD, open jaw type. He was diagnosed as PSP
at 2014, and prescribed many medicines since then. He was suffering from constant opened jaw, which results in poor mastication,
dry mouth and impaired communication. However, there was no response on medications. The patient was treated with injection
of botulinumA toxin (Botox) at the lateral pterygoids and the anterior digastrics muscles involved in jaw opening dystonia using
ultrasonography. The patient was treated with injections of total 25 units of botulinumA toxin at two points in each lateral pterygoid
muscle, and in two points of each anterior digastric muscle of total 25 units at both sides.
Results:
Before the procedure, the patient showed constant open jaw state with an impossible of speaking and feeding. After
the procedure, the patient showed much improved jaw movement with voluntary jaw movements and even full closed jaw. The
improvement was manifested 6 days later after the procedure, and there has been no report of severe side effect after botulinum toxin
injection.
Conclusion:
Botulinum toxin is a potent neuromuscular paralyzing agent, which cause reversible chemodenervation by blocking
the presynaptic release of acetylcholine. In this regards, this case suggested that botulinum toxin A has been proved to be effective in
focal dystonia.
Biography
Jin Seok Seo has completed his MD at the age of 26 years from Kyunghee University School of Medicine. He is a physical medicine and rehabilitation doctor of Veterans
Health Service Medical Center, Seoul, Korea.
elfscastle@hanmail.netJin Seok Seo, J Pain Relief 2017, 6:6 (Suppl)
DOI: 10.4172/2167-0846-C1-018