alexa Abdominal Wall and Intra Pelvic Hematoma Presenting as Abdominal Pain after Short Course of Antibiotics in Patients on Long Term Warfarin Therapy
ISSN: 2329-6607

Cardiovascular Pharmacology: Open Access
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Case Report

Abdominal Wall and Intra Pelvic Hematoma Presenting as Abdominal Pain after Short Course of Antibiotics in Patients on Long Term Warfarin Therapy

Kandegedara Ruwana Munasinghe1*, Gallage Chandima Amarasena2, Naomali Lalani Amarasena1 and Harshana Dilan Samarasinghe1

1Advanced Cardiology Unit, Sri Jayewardenepura Hospital, Sri Lanka

2Cardiothoracic Unit, National Hospital of Sri Lanka, Sri Lanka

*Corresponding Author:
Kandegedara Ruwana Munasinghe
Advanced Cardiology Unit
Sri Jayewardenepura Hospital, Sri Lanka
Tel: 94718339509
E-mail: [email protected]

Received Date: August 19, 2016; Accepted Date: January 11, 2016; Published Date: January 18, 2016

Citation: Munasinghe KR, Amarasena GC, Amarasena NL, Samarasinghe HD(2016) Abdominal Wall and Intra Pelvic Hematoma Presenting as Abdominal Pain after Short Course of Antibiotics in Patients on Long Term Warfarin Therapy.Cardiovasc Pharm Open Access 5:170. doi:10.4172/2329-6607.1000170

Copyright: © 2016 Munasinghe KR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Warfarin is the most commonly used anticoagulant in clinical practice. Despite its advantages it has serious side effects mainly bleeding due to narrow therapeutic range and several drug and food interactions. Spontaneous abdominal haemorrhage is one of the rare bleeding manifestations of it. Concomitant use of commonly used antibiotic are associated with an increased risk of bleeding among patients receiving warfarin. We report two patients who presented with abdominal pain, later confirmed as abdominal wall and intraabdominal hematoma by computed tomography of abdomen. Both of them were had concomitant use of antibiotics along with warfarin prior to this clinical presentation. We highlight the importance of making a high degree of suspicion on abdominal haemorrhage in patients with warfarin treatment when presented as abdominal abdomen. We also emphasized the consideration of drug interaction of warfarin before prescribing other medication as well as close monitoring of INR during that period

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