alexa Anti-Thrombotic Therapy: Implications for Invasive Outp
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
Open Access

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Review Article

Anti-Thrombotic Therapy: Implications for Invasive Outpatient Procedures in Dentistry

Hong CH1* and Islam Intekhab2

1Discipline of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, National University of Singapore, Singapore

2Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Singapore, Singapore

*Corresponding Author:
Hong CH
Discipline of Orthodontics and Pediatric Dentistry
Faculty of Dentistry, National University of Singapore
5 Lower Kent Ridge Road 119074, Singapore
Tel: +65-779-5555
Fax: +65 6773 2602
E-mail: [email protected]

Received date: August 03, 2013; Accepted date: October 16, 2013; Published date: October 22, 2013

Citation: Hong CH, Islam I (2013) Anti-Thrombotic Therapy: Implications for Invasive Outpatient Procedures in Dentistry. J Blood Disord Transfus 4:166. doi: 10.4172/2155-9864.1000166

Copyright: © 2013 Hong CH, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



This article reviews the implications of traditional and novel anti-thrombotic medications in dentistry, focusing on areas relating to the prevalence of significant post procedure bleeding, measures that should be taken to minimize and manage bleeding; and current opinions regarding need for alteration of anti-thrombotic regimens prior to dental procedures in dentistry. Based on the current literature, discontinuation of anti-platelet medications, warfarin therapy, dabigatran and Factor Xa inhibitors is not needed in majority of in office dental procedures. However, it is important that treating clinician must use discretion based on the patient’s risk profile (e.g. presence of comorbidities) and extensiveness of planned dental procedures to assess each patient’s risk for significant bleeding.


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