alexa Bacterial Carbon Storage to Value Added Products
ISSN: 1948-5948

Journal of Microbial & Biochemical Technology
Open Access

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Research Article

Bacterial Carbon Storage to Value Added Products

Christopher J. Brigham1, Kazuhiko Kurosawa1, ChoKyun Rha2 and Anthony J. Sinskey1,3,4*

1Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139

2Biomaterials Science and Engineering Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Avenue,Cambridge,MA 02139

3Engineering Systems Division, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139

4Health Sciences Technology Division, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139

*Corresponding Author:
Christopher J. Brigham
Department of Biology
Massachusetts Institute of Technology
77 Massachusetts Avenue
Cambridge, MA, USA
Tel: +1-617-253-6721
Fax: +1-617-253-8550
E-mail: [email protected]

Received date: September 23, 2011; Accepted date: December 01, 2011; Published date: December 06, 2011

Citation: Brigham CJ, Kurosawa K, Rha C, Sinskey AJ (2011) Bacterial Carbon Storage to Value Added Products. J Microbial Biochem Technol S3:002. doi:10.4172/1948-5948.S3-002

Copyright: © 2011 Brigham CJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Microorganisms have evolved different systems for storing carbon during times of stress. In the cell’s natural environment, the stored carbon can then be utilized for growth when other nutrients are in better supply. Storage of carbon and other nutrients is ubiquitous throughout the prokaryotic and eukaryotic domains of life. These carbon storage molecules have great industrial importance. They can be useful as value-added products, as either biopolymers or biofuels, and cells are grown in large quantities and these compounds are harvested, usually as a replacement for a petroleum-based product. Nowadays, entire industries have been generated based on the production and utilization of these compounds. We focus on two bacteria that could be considered paradigms of their particular carbon storage strategy: Ralstonia eutropha and Rhodococcus opacus . R. eutropha has been well-studied as a polyhydroxyalkanoate (bioplastic) producer and R. opacus is a model bacterium for high yield triacylglycerol (TAG) production for biofuels. Both species produce carbon storage molecules that can potentially diminish our reliance on fossil-based petroleum. However, in both cases, there are challenges that must be overcome before profitable production schemes are established using these organisms. We explore the previous and current works to address these challenges in this review.


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