alexa Cardioprotective Potential of Baicalein: A Short Review of In Vitro and In Vivo Studies | OMICS International | Abstract
ISSN : 2153-2435

Pharmaceutica Analytica Acta
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Review Article

Cardioprotective Potential of Baicalein: A Short Review of In Vitro and In Vivo Studies

Chen Bao-An1,2*,Ravichandran Senthilkumar1,2,Fu Rong3 and Qing long Guo3

1Department of Neoplastic Hematologic Disorders (Medical Science Key Subject of Jiangsu Province),Zhongda Hospital,Schoool of Medicine,Southeast University, Nanjing 210009, P.R. China;

2Department of Oncology,School of Medicine,Southeast University,Nanjing 210009,P.R. China

3State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Carcinogenesis and Intervention,China Pharmaceutical University,24 Tongjiaxiang,Nanjing 210009,P.R. China

*Corresponding Author:
Chen Bao-An
Department of Oncology
School of Medicine, Southeast University
Nanjing 210009, P.R. China
Tel: 86-25-83272006
Fax: +86-25-83272011
E-mail: [email protected]

Received date: December 04, 2013; Accepted date: January 03, 2014; Published date: January 09, 2014

Citation: Bao-An C, Senthilkumar R, Rong F, Guo QL (2014) Cardioprotective Potential of Baicalein: A Short Review of In Vitro and In Vivo Studies. Pharm Anal Acta 5:280. doi: 10.4172/2153-2435.1000280

Copyright: © 2014 Bao-An C, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Many plant-derived natural components have been recognized as effective in the treatment of human diseases. Baicalein (5,6,7-trihydroxyflavone) is one of the primary active components of Scutellaria species, and is well known ingredient in traditional Chinese medicine (TCM) and oriental medicine. Numerous studies have reported that baicalein possesses multiple pharmacological functions, such as anticancer, antioxidant, anti-inflammatory, neuroprotective, hepatoprotective, and antimicrobial properties. The cardioprotective effect of baicalein has been proved in several cell culture and small animal models. This review addresses the recent findings of cardioprotective potentials of baicalein in vitro and in vivo

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