alexa Complexity and Entropy Analysis of DNA Methyltransferase | OMICS International | Abstract
ISSN: 2153-0602

Journal of Data Mining in Genomics & Proteomics
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Complexity and Entropy Analysis of DNA Methyltransferase

Xiaoli Xie1,2, Ying Yu2, George Liu3, Zhifa Yuan1 and Jiuzhou Song2*

1College of Science, Northwest A&F University, Yangling, 712100 P. R. China

2Department of Animal & Avian Sciences, University of Maryland, College Park, MD 20742, USA

3BFGL-ANRI, ARS, USDA, BARC-East, Beltsville, MD 20705-2350

*Corresponding Author:
Dr. Jiuzhou Song
Department of Animal & Avian Sciences
University of Maryland, College Park, MD 20742, USA
Tel: (301) 405-5943
Fax: (301) 405-7980
Email: [email protected]

Received date: November 28, 2010; Accepted date: December 27, 2010; Published date: December 30, 2010

Citation: Xie X, Yu Y, Liu G, Yuan Z, Song J (2010) Complexity and Entropy Analysis of DNA Methyltransferase. J Data Mining in Genom Proteomics 1:105. doi:10.4172/2153-0602.1000105

Copyright: © 2010 Xie X, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Background: The application of complexity information on DNA sequence and protein in biological processes are well established in this study. Available sequences for DNMT1 gene were thoroughly explored in the information complexities. DNMT1 gene is a maintenance methyltransferase responsible for copying DNA methylation patterns to the daughter strands during DNA replication in different species. Results: We found that the entropy of DNMT1 gene in different species is DNA base composition dependent, and its complexity in mammals is lower in introns than in coding regions. We also demonstrated the impacts of entropy on domains and non-domain(s) of the DNMT1 gene. The results from DNA and protein sequences indicated that DNA evolution has a tendency toward complexity. The most interest is that the methylation’s changes of the gene over aging in a unique chick model showed aging-driven entropy characteristics, which may give an explanation of aging processes. Conclusion: In summary, the information complexity of DNMT1 gene is related to its genomic composition, which thereby associates to evolutionary and aging processing, even though the intrinsic mechanism is not to be studied yet.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7