alexa Does the Zinc Neuroprotective Effectiveness of Mean Prevention of Intracellular Zinc Accumulation in Water in INDIA | OMICS International | Abstract
ISSN : 2153-2435

Pharmaceutica Analytica Acta
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Review Article

Does the Zinc Neuroprotective Effectiveness of Mean Prevention of Intracellular Zinc Accumulation in Water in INDIA

Shuvam Agarwal*

Department of Pathophysiology, Pune University, India

*Corresponding Author:
Shuvam Agarwal
Department of Pathophysiology, Pune University, India
E-mail: [email protected]

Received Date: April 27, 2012; Accepted Date: August 13, 2012; Published Date: August 17, 2012

Citation: Agarwal S (2012) Does the Zinc Neuroprotective Effectiveness of Mean Prevention of Intracellular Zinc Accumulation in Water in INDIA. Pharmaceut Anal Acta 3:163. doi: 10.4172/2153-2435.1000163

Copyright: © 2012 Agarwal S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Zinc (Zn) plays an important role in the activity of all cells, including neurons. Both the neurotoxic and neuroprotective effects of zinc have been well established, but the exact mechanism of its dual abilities still remains unclear. The same effect may also be found in other cells, but it should be remembered that lower sensitivity to hypoxia prolongs in time the cytotoxic effect of Zn+2 excess.
It seems that the apparent dualism depends primarily on the energetic condition of the cell, and also on the efficacy of ion pumps, genetically conditioned mechanisms regulating Zn cell efflux and Zn sequestration inside the cell and also on the concentration of extracellular free Zn.

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