alexa Effects of Persistent Allergic Rhinitis on Spirometric
ISSN: 2155-6121

Journal of Allergy & Therapy
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Research Article

Effects of Persistent Allergic Rhinitis on Spirometric Parameters

Majid Jafari*

Allergy Research Center, Ghaem Hospital, Mashhad, Iran

*Corresponding Author:
Majid Jafari
Allergy Research Center, Ghaem Hospital, Mashhad, Iran
Tel: +98(513) 8012827, +98(912)2422776
E-mail: [email protected]

Received date: September 15, 2016; Accepted date: October 09, 2016; Published date: October 19, 2016

Citation: Jafari M (2016) Effects of Persistent Allergic Rhinitis on Spirometric Parameters. J Allergy Ther 7:242. doi: 10.4172/2155-6121.1000242

Copyright: © 2016 Jafari M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background: Allergic rhinitis (AR) is an inflammatory process due to allergens. The relation between AR and inflammation of lower airways is documented. However, AR is considered as the strong risk factor for the onset of asthma in adults. Methods: This prospective cross sectional study carried out on 126 patients with perennial allergic rhinitis (PAR). Clinical examination, skin prick test and spirometry maneuver were performed in all patients. Results: Our results showed that there is a significant difference between forced expiratory flow at 25% and 75% of the pulmonary volume (FEF 25.75). <80% of the predicted for PAR (P=0.003). There were no significant differences among patients with forced vital capacity (FVC)<80% of predicted and forced expiratory volume in the first second( FEV1 )<80% of the predicted, for PAR respectively (P>0.05, P=0.08). Furthermore, in patients who were sensitive to indoor allergens, FEF25-75<80% of the predicted was more impaired (P=0.003). There was a negative correlation between FEF25-75 and the duration of disease (r=-0.13). Conclusion: This study highlights some risk factors such as the duration of PAR, age, indoor allergens and FEF25-75 as a marker of early bronchial involvement in patients with moderate-to severe and PAR alone.


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