Evaluation of Free Radical Scavenging Activity of Various Leaf Extracts from Kedrostis foetidissima (Jacq.) Cogn.,
Vadivukkarasi Sasikumar* and Pavithra Kalaisezhiyen
Department of Biochemistry, KSR College of Arts and Science, Thokkavadi, Tiruchengode, Tamilnadu, India
- *Corresponding Author:
- Sasikumar V
Department of Biochemistry
KSR College of Arts and Science
Thokkavadi, Tiruchengode, Tamilnadu, India
E-mail: [email protected]
Received Date: Febuary 28, 2014; Accepted Date: April 22, 2014; Published Date: May 5, 2014
Citation: Sasikumar V, Kalaisezhiyen P (2014) Evaluation of Free Radical Scavenging Activity of Various Leaf Extracts from Kedrostis foetidissima (Jacq.) Cogn.,. Biochem Anal Biochem 3:150. doi: 10.4172/2161-1009.1000150
Copyright: © 2014 Sasikumar V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The present study was to compare the effect of in vitro free radical scavenging activity between the various leaf extracts (aqueous, methanol, acetone chloroform and petroleum ether) of Kedrostis foetidissima. The free radical scavenging activity was found to be high in methanolic extract for DPPH, hydroxyl, nitric oxide, superoxide,hydrogen peroxide(H2O2) radical in a concentration dependent manner followed by chloroform, aqueous, acetone and petroleum ether extracts. The metal chelating activity and reducing power ability was also similar as above. The content of total phenols, flavonoids and tannins was also found to be high in methanolic extract which may be correlated to its antioxidant activity. Thus the result suggests that the methanolic leaf extract of K.foetidissima could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical induced diseases.