Mesenchymal Stem Cells: The New Players in the Pathogenesis of Tuberculosis
Division of infectious Diseases, Childrens Hospital Los Angeles, Los Angeles, CA 90027 USA
- *Corresponding Author:
- Dr. Rahul Mittal
Division of Infectious Diseases
MS#51,,Childrens Hospital Los Angeles
4650 Sunset Boulevard
Los Angeles, CA, 90027, USA
Tel.: +1 323-361-5809
E-mail: [email protected]
Received Date: February 03, 2011; Accepted Date: February 10, 2011; Published Date: April 29, 2011
Citation: Mittal R (2011) Mesenchymal Stem Cells: The New Players in the Pathogenesis of Tuberculosis. J Microbial Biochem Technol 3: ii-0. doi:10.4172/1948-5948.100000e3
Copyright: © 2011 Mittal R. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Tuberculosis (TB) is the most common and deadly infectious disease associated with significant mortality and morbidity [1,2]. TB is the second highest cause of mortality from an infectious agent accounting for 2 million deaths each year . There are more than 9 million new cases of TB every year worldwide, and incidence is declining only at a rate of less than 1% per year . Mycobacterium tuberculosis (M. tb) is the causative agent of TB, which is transmitted through aerosol droplets that are inhaled by the host and deposited in the lung which become the reservoir of infection [5-7]. A recent surge in the antibiotic resistant strains of M. tb has further complicated the treatment of this deadly disease [8-11]. Lack of understanding about the pathogenesis of the disease has hindered the development of effective preventive strategies against this fatal disease.