alexa Molecular Characterization and Expression Pattern of a Liver-Expressed Antimicrobial Peptide 2 (LEAP-2) Gene in Yellow Catfish (Pelteobagrus fulvidraco) | Abstract
ISSN: 2155-9546

Journal of Aquaculture Research & Development
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Molecular Characterization and Expression Pattern of a Liver-Expressed Antimicrobial Peptide 2 (LEAP-2) Gene in Yellow Catfish (Pelteobagrus fulvidraco)

Gang Ren1,2, Wen-Ying Shen1*, Wei-Fen Li2 and Yao-rong Zhu1

1Department of Biology, College of Life Science, Shaoxing University, Shaoxing 312000, China

2College of Animal Sciences, Zhejiang University, Hangzhou 310058, China

*Corresponding Author:
Wen-Ying Shen
Department of Biology, College of Life Science
Shaoxing University, Zhejiang province
312000, People’s Republic of China
Tel: +86 575 88345863
Fax: +86 575 88345012
E-mail: [email protected]

Received Date: March 18, 2014; Accepted Date: April 23, 2014; Published Date: April 30, 2014

Citation: Ren G, Shen WY, Li WF, Zhu YR (2014) Molecular Characterization and Expression Pattern of a Liver-Expressed Antimicrobial Peptide 2 (LEAP-2) Gene in Yellow Catfish (Pelteobagrus fulvidraco). J Aquac Res Development 5:229. doi:10.4172/2155-9546.1000229

Copyright: © 2014 Ren G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


Liver-expressed antimicrobial peptide 2 (LEAP-2) is a member of antimicrobial peptides, which acts as an
important component of the host innate immune system and plays a crucial role in host defense against microbial invasion. In this study, a LEAP-2 gene (PfLEAP-2) was amplified from the liver of yellow catfish (Pelteobagrus fulvidraco) by reverse transcription PCR. The length of P LEAP-2 open reading frame was 282 bp, which encode 94 amino acids (aa) including a 28-aa signal peptide, a 21-aa prodomain, and a 45-aa mature peptide. The results of tissue distribution showed that PfLEAP-2 mRNA was mainly expressed in the gill, skin, stomach, and head kidney. The significant up-regulation of PfLEAP-2 in liver after 4 hours of challenge of Edwardsiella tarda suggested, PfLEAP-2 might play an important role in the early immune defense of the yellow catfish against bacterial pathogen


Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


porn sex

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

Gaziantep Escort

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A


[email protected]

1-702-714-7001Extn: 9037


James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

mp3 indir

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals


Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T


[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version