alexa Nanoparticles as Emerging Therapeutics for Coping Antimicrobial Drug Resistance
ISSN: 2167-7662

Bioenergetics: Open Access
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Review Article

Nanoparticles as Emerging Therapeutics for Coping Antimicrobial Drug Resistance

Navnit Kumar Mishra*

Department of Biotechnology, Engineering Block – II, Maharishi Markandeshwar University, Ambala, India

*Corresponding Author:
Mishra NK
Assistant Professor, Department of Biotechnology, Engineering Block – II
Maharishi Markandeshwar University, Ambala - 133207, INDIA
Tel: +91 8901432252
E-mail: [email protected]

Received date: January 10, 2017; Accepted date: March 25, 2017; Published date: March 29, 2017

Citation: Mishra NK (2017) Nanoparticles as Emerging Therapeutics for Coping Antimicrobial Drug Resistance. Bioenergetics 6:150. doi: 10.4172/2167-7662.1000150

Copyright: © 2017 Mishra NK. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Emergence of antimicrobial drugs resistance to traditional antibiotic compounds is a global problem with considerable challenges predict ted for treatment of many serious bacterial infections. The drug resistance against common antibiotics has gain resurgence in developing novel therapeutics such as nanoparticles against microbe. Some nanoparticles have been observed previously to have antimicrobial properties. Although the biological basis for this effect is currently unknown, it is hypothesized that quantum interactions within the cell play vital role in the regulation of RNA transcription relating to both coding (relating to genes) and non-coding (structural RNA) regions of the genome. These transcripts interact and establish an intracellular communication in the bacterium Escherichia coli. Their interaction can be unfolded by the application of nanoparticles. The response in terms of bacterial growth and RNA expression upon the exposure of the nanoparticles can be evaluated. Furthermore, the site of nanoparticle incorporation within the bacterial cell and the potential intracellular transcript interactions has been hypothesized.

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