Journal of Carcinogenesis & Mutagenesis

Abstract

Successful Treatment of CD30+Lymphomatoid Papulosis using a 308-nm Excimer Light

Akiko Watabe, Taku Fujimura, Sadanori Furudate and Setsuya Aiba

We describe a 61-year-old Japanese patient with Lymphomatoid papulosis (LYP) successfully archived complete remission, using a 308-nm Excimer light. Interestingly, immunohistochemical staining revealed that CD30⁺ anaplastic tumor cells were surrounded by CD163⁺ macrophages and CCL18 producing cells, both of which were reported to correlate with the prognosis of CTCL. Our present study sheds light on the possible pathogenesis of LYP and the possibility of a 308-nm Excimer light phototherapy for LYP.