alexa The Clinical Utility of Circulating Microparticlesâ
ISSN: 2329-6925

Journal of Vascular Medicine & Surgery
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Review Article

The Clinical Utility of Circulating Microparticles’ Measurement in Heart Failure Patients

Berezin AE*

Consultant of Therapeutic Unit, Internal Medicine Department, State Medical University of Zaporozhye, Ukraine

*Corresponding Author:
Berezin AE
Professor, MD, PhD
Consultant of Therapeutic Unit
Internal Medicine Department
State Medical University of Zaporozhye
26, Mayakovsky av, Zaporozhye, UA-69035, Ukraine
Tel: +380612894585
E-mail: [email protected]; [email protected]

Received Date: May 13, 2016; Accepted Date: May 26, 2016; Published Date: June 06, 2016

Citation: Berezin AE (2016) The Clinical Utility of Circulating Microparticles’ Measurement in Heart Failure Patients. J Vasc Med Surg 4:277. doi:10.4172/2329-6925.1000277

Copyright: © 2016 Berezin AE. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Heart failure (HF) continues to have a sufficient impact on morbidity, mortality and disability in developed countries. Growing evidence supports the hypothesis that microparticles (MPs) might contribute to the pathogenesis of the HF development paling a pivotal role in the regulation of the endogenous repair system, thrombosis, coagulation, inflammation, immunity and metabolic memory phenomenon. Therefore, there is a large body of data clarifying the predictive value of MP numerous in circulation among subjects with HF. Although determination of MP signature is better than measurement of single MP circulating level, there is not yet closely confirmation that immune phenotype of cells produced MPs are important for HF prediction and development. The aim of the review: to summarize knowledge regarding the measurement of number of various MPs subsets in HF patients.

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