alexa The Immunogenicity of Peptoid-Protein Conjugates
ISSN: 2157-7560

Journal of Vaccines & Vaccination
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Short Communication

The Immunogenicity of Peptoid-Protein Conjugates

Allison Case1,2#, Angela Desmond1,3#, Daniel Lopes1,4, Kelly Dye1,5, Kelly Mapes1,6, Stephen Ruback1, Iliodora Pop1,7, Jiyeun Kate Kim1,8, Pavitra Chakravarty1, Joan E. Smallshaw1, Laurentiu M. Pop1,9 and Ellen S.Vitetta1,10*

1Cancer Immunobiology Center and Department of Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

2Department of Bioengineering, The University of Texas at Dallas, Texas, USA

3Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA

4Eli Lilly, Indianapolis, Indiana, USA

5School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA

6Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

7Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas, USA

8College of Pharmacy, Pusan National University, Busan, Republic of Korea

9Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA

10Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

#Authors are equally contributed to this work.

*Corresponding Author:
Ellen S. Vitetta
Cancer Immunobiology Center and Department of Immunology
University of Texas Southwestern Medical Center
Dallas, Texas, USA
E-mail: [email protected]

Received date: June 20, 2016; Accepted date: July 06, 2016; Published date: July 11, 2016

Citation: Case A, Desmond A, Lopes D, Dye K, Mapes K, et al. (2016) The Immunogenicity of Peptoid-Protein Conjugates. J Vaccines Vaccin 7:329. doi: 10.4172/2157-7560.1000329

Copyright: © 2016 Case A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

We demonstrate that a peptoid composed of five monomers and attached via a maleimide linker to a carrier protein elicits anti-peptoid, anti-linker and anti-carrier antibodies in rabbits. Specific anti-peptoid antibodies were affinity purified and used to reproducibly retrieve three specific peptoid-coupled beads from 20,000 irrelevant peptoid-beads using magnetic screening.

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords