The remineralization of the artificial Â“white spotÂ” lesions Â– experimental research
Aim: to investigate the remineralization of the artificial white spot lesions under different conditions:
in vitro and in situ.
Materials and Methods:
To induce the dental lesions, the bucal surfaces of 20 sound premolar teeth were treated for 1 minute
with H3PO4 37%. For the first (in vitro) study, the teeth were divided into two groups: the first one
was immersed in artificial saliva, and the second - in artificial saliva with F", at a neutral pH in the
first experimental week, and at a low pH (5.5) in the second experimental week. After each week one
tooth was removed from each solution for a clinical examination and a chemical analysis of the
solutions was made. For the second (in situ) study the teeth were sectioned in two halves, one being
fixed in an orthodontic appliance, and the other half being the control one. After two weeks, a clinical
examination of the teeth was made.
Results: the remineralization of the white spot lesions in saturated solutions in calcium-phosphate -
as the artificial and natural saliva - is a common phenomenon and is stimulated by the presence of
fluoride ions, especially at alow pH.
Conclusion: the remineralization in situ is significantly more effective than the remineralization in