alexa The Second Case of Death in the Same Family from Chronic Renal Failure and Systemic Oxalosis as a Result of Primary Hyperoxaluria Type1
ISSN: 2161-1041

Hereditary Genetics: Current Research
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Case Report

The Second Case of Death in the Same Family from Chronic Renal Failure and Systemic Oxalosis as a Result of Primary Hyperoxaluria Type1

Jamal Qasem Abumwais*

Ministry of Education and Higher Education, Jenin, Palestine

*Corresponding Author:
Jamal Qasem Abumwais
Ministry of Education and Higher Education
Jenin, Palestine
Tel: 0097242518312, 00972599072538
E-mail: [email protected]

Received Date: October 29, 2013; Accepted Date: December 16, 2013; Published Date: December 18, 2013

Citation: Abumwais JQ (2013) The Second Case of Death in the Same Family from Chronic Renal Failure and Systemic Oxalosis as a Result of Primary Hyperoxaluria Type1. Genetics 2:121. doi: 10.4172/2161-1041.1000121

Copyright: © 2013 Abumwais JQ. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 

Abstract

Background: Primary hyperoxaluria is a rare cause of chronic renal failure in children worldwide, but it is an important cause of chronic renal failure among children under 15 years old in Jenin district (Palestine) contributing about 67% of the causes of chronic renal failure among these children as was found in a previous study. The infantile form of hyperoxaluria manifests early with nephrocalcinosis and leads to end-stage renal failure in early childhood and the most severe form may lead to death during the first year of life. Case presentation: We report the case of a 8-years old boy with a history of primary hyperoxaluria type1 since the age of three months presented with ascites, generalized edema, fever, myopathy, limited movement ability, general malaise, severe malnutrition, and respiratory difficulties. Clinical, laboratory, ultrasound, cardiac investigations revealed end-stage renal failure accompanied by heart failure, liver failure, liver cirrhosis, and systemic oxalosis. The patient was in a bad condition, stayed 4 days in the ICU and died in the fourth day from complications of systemic oxalosis.
Conclusion: History revealed that this is the second case of death in the same family from ESRD and complications of primary hyperoxaluria. The first death was for his brother since about 10 years who died at age of three months.
It seems that the primary hyperoxaluria type 1 in this family is very severe and leads to end-stage renal disease and systemic oxalosis in early childhood despite conservative treatment. Since, sometimes, there are more than one case of primary hyperoxaluria in the same family, all children in the family with a history of primary hyperoxaluria - even who looks like healthy - must be screened for the disease because early diagnosis is important in treating strategies and delaying complications such as end-stage renal disease and systemic oxalosis.

Share This Page

Additional Info

Loading
Loading Please wait..
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords