alexa Vaccine Immunotherapy Strategies in Colorectal Cancer Treatment
ISSN: 2168-9431

Single Cell Biology
Open Access

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Review Article

Vaccine Immunotherapy Strategies in Colorectal Cancer Treatment

Elena Niccolai1 and Amedeo Amedei1,2*
1Department of Internal Medicine, University of Florence and Department of Biomedicine, Patologia Medica Unit, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy
2Center of Oncologic Minimally Invasive Surgery, University of Florence, Florence, Italy
Corresponding Author : Dr. Amedeo Amedei
Department of Internal Medicine
Division of Immunonology
University of Florence
Viale Pieraccini, 6, 50134 Firenze, Italy
Tel/Fax: +390554271495
E-mail: [email protected]
Received May 05, 2012; Accepted June 30, 2012; Published July 02, 2012
Citation: Niccolai E, Amedei A (2012) Vaccine Immunotherapy Strategies in Colorectal Cancer Treatment. Single Cell Biol 1:102. doi: 10.4172/2168-9431.1000102
Copyright: © 2012 Niccolai E, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
 

Abstract

The colorectal cancer (CRC) is a most frequent cause of cancer-related deaths. Surgical tumor resection remains the primary curative treatment for CRC but nearly 50% of patients with macroscopic clearance of the tumor by surgery relapses. For this purpose new complementary treatments, such as immunotherapy, are being explored. In this article, we analyze and discuss the clinical immunotherapy vaccine studies performed in patients treated for colorectal cancer.

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