alexa Assessment Of Coagulation Profile, Fibrinogen, Protein C, Protein S, Antithrombin, And Vitamin K Levels Among Sudanese Neonates With Proven Sepsis In Omdurman Maternity Hospital, Sudan | 64886
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

7th World Hematologists Congress

Albara Abdulfatah Mohammed
University of Khartoum, Sudan
ScientificTracks Abstracts: J Blood Disord Transfus
DOI: 10.4172/2155-9864-C1-022
Abstract
Aim: Neonatal sepsis is lethal disease represents one of the most common causes of neonatal morbidity and mortality worldwide. Aim of this study is to assess platelets count, prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen, protein C, protein S, antithrombin (AT) and vitamin K (VK) in Sudanese septic neonates and compare them with healthy neonates in order to study hemostatic alteration among septic neonates. Methods: Prospective study was conducted in Omdurman Maternity Hospital in the period June 2013 to April 2015 on total of 100 samples divided into case and control group (50 for each). Blood culture was done routinely for all neonates with suspected sepsis; the first 50 neonates with a positive culture were taken as case group. Platelets were counted by cell counter haematology analyzer Sysmex KX-21. PT, APTT, TT, fibrinogen, PC and PS were assessed by clotting procedure via coagulometer Stago Start four. AT assessed spectrophotometrically by turbidimetric method via chemistry analyzer Mindray BA-88A. VK assessed by the Schmiatzu.10 ADVP. Data were tabulated; means were compared and analyzed by SPSS20 via one sample t test. Results: In case group, 17 neonates underwent early onset sepsis (0-7 days) and 33 late onsets (7-28 days). In the outcome, 10 neonates were died. Means of platelets count, PT, APTT, TT, fibrinogen, PC, PS, AT and VK were 60,289 c/mm3, 16.6 s, 47.8 s, 18.6 s, 482.2 mg/dl, 34.4%, 33.4%, 183.9 mg/ml and 0.86 ng/ml; and 212,030 c/mm3, 13.9 s, 37.5 s, 20.6 s, 393.7 mg/dl, 36.8%, 34.7%, 221.5 mg/ml and 1.23 ng/ml for case and control respectively. Conclusions: Platelets count significantly decreased, PT and APTT significantly prolonged, TT significantly shorted, fibrinogen significantly increased and AT significantly decreased in neonatal sepsis. APTT and PC showed significant correlation with outcome, so both can predict early mortality, PT and TT showed significant correlation with early sepsis.
Biography

Albara Abdulfatah Mohammed has completed his PhD at University of Khartoum, Sudan; BSc and MSc at University of Medical Sciences and Technology. He is the Coordinator of Medical Laboratories Sciences Program at Alfajr College. His research interest is in Hemostasis.

Email: [email protected]

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7