alexa Control And Manipulation Of A Charged Macromolecule In A Nanosized Gap Between Two Fluid Reservoirs
ISSN: 2157-7439

Journal of Nanomedicine & Nanotechnology
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading Please wait..

4th International Conference on Nanotek & Expo
December 01-03, 2014 DoubleTree by Hilton Hotel San Francisco Airport, USA

Venkat S K Balagurusamy
ScientificTracks Abstracts: J Nanomed Nanotechnol
DOI: 10.4172/2157-7439.S1.017
Biomolecules and therefore living systems indispensably depend on the water environment for their survival and functioning. The ability of some biological assemblies like DNA or RNA polymerases to move along information-carrying polymers of nucleic acids with single nucleotide precision in water is vital for the machinery of life in order to replicate them correctly. Controlling the position of a macromolecule like DNA at single monomer accuracy is of great technological importance as well for developing high-speed electronic DNA sequencing devices. We use a simple born ion continuum model to analyze the effect of solvation energy change on the translocation of a charged linear polymer molecule through a nanosized vapor gap between two fluid reservoirs. As the effective radius of the discretely spaced charges increases, our model predicts a transition from trapping to the diffusion of the molecule in the vapor gap. We present results of creating such a nanogap achieved by a new experimental technique that uses an FPGA-driven nanopositioner, triggered by the entry of a DNA molecule at the constriction of the nanopipette. The developed platform will enable testing some of our recent theoretical predictions and has the potential for applications in biomolecular sensing.
image PDF   |   image HTML
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version