Journal of Clinical & Experimental Pharmacology

Evaluation of the antioxidant and anti-inflammatory activities of Lactobacillus casei grown on black rice

Co-organized Event International Conference on Toxicology and Clinical Pharmacology & 2^nd International Conference on Generic Drugs and Biosimilars

December 14-16, 2017 Rome, Italy

Young Min Lee

Konkuk University, Republic of Korea

Posters & Accepted Abstracts: Clin Exp Pharmacol

Abstract:

Black rice and its pigment fraction have been known for their many beneficial effects to our body because it contains several chemical compounds that act as antioxidant and anti-inflammatory agents. The aim of this study was to investigate the effect of Lactobacillus casei grown on black rice ethanol extract on antioxidant and anti-inflammatory activity. The phenolic and flavonoid content were168.7±2.70 mg GAE/100g of dry mass and 214.38±16.77mg CE/100g of dry mass, respectively. Lactobacillus casei grown on black rice ethanol extract showed high DPPH and ABTS radical scavenging activities as well as increased ROS inhibition, reducing power, and DNA protection. The extract exhibited nontoxic (up to 500ug/ml) on RAW 264.7 cells treated with or without LPS and suppressed LPS-induced NO formation in RAW 264.7 macrophages. The results of this study revealed that the Lactobacillus casei grown on black rice ethanol extract showed notable antioxidant and antiinflammatory properties with potential use in nutraceutical or functional food formulations.

Biography :

Young Min Lee completed Master’s course in the Department of Life Science in Konkuk University, Glocal Campus, South Korea. His interests include Food and Medical Research. He is currently pursuing Doctor course in Applied Life Science