Pharmaceutica Analytica Acta

Formulation and evaluation of neutraceutical tablets of lyophilized nanoparticles of Zinc and Asparagus extracts

5^th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems

March 16-18, 2015 Crowne Plaza, Dubai, UAE

Sandeep Arora, Mansi Chitkara, I S Sandhu and Shreea Sharma

Posters & Accepted Abstracts: Pharm Anal Acta

Abstract:

Herbal ZnO nanoparticles were synthesized using Asparagus root extract via co precipitation methods. The synthesized nanostructures were characterized by XRD, SEM and TEM which reveal the formation of crystalline ZnO nano-structures and spherical and granular nature with characteristic peaks of ZnO nanoparticles. The nanoparticles of Zinc and extract were also standardized for herbal marker component and Zinc and then tablet formulations were developed and standardized for formulation parameters. It was observed that the nanoparticles offered a spherical and granular nature, which offered very convenient advantage by producing very good preformulation characters including flow and particle size as compared to taking dry herbal powder as such which produce great difficulty in tableting. The formulated tablets were standardized for formulation parameters on the basis of evaluation characteristics including disintegration time, dissolution time, friability and content for use as herbal nutraceuticals tablets and further development using various extracts.