alexa G- Protein Coupled Receptors Control Neutrophil Chemotaxis
ISSN: 2155-9864

Journal of Blood Disorders & Transfusion
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

International Conference on Hematology & Blood Disorders
September 23-25, 2013 DoubleTree by Hilton Hotel Raleigh-Durham Airport at RTP, NC, USA

Xuehua Xu
ScientificTracks Abstracts: J Blood Disord Transfus
DOI: 10.4172/2155-9864.S1.002
Abstract
Chemotaxis of leucocytes, chemokine mediated directional cell migration, plays essential roles in innate immunity and also in metastasis of cancer cells. Efficient chemotaxis requires a precise coordination of polymerization and depolymerization of the actin cytoskeletonat leading fronts of migrating cells. GPCR activation initiates multiple signaling pathways ultimately to control polymerization of F-actin based cytoskeleton. However, how GPCR activation mediates the depolymerization of F-actin largely remains elusive. Here, we show the essential role of protein kinase D (PKD) in neutrophil chemotaxis and its underling molecular mechanism.
Biography
Xuehua Xu has completed his Ph.D. from Tsukuba University, Japan, in 2002 and did postdoctoral studies in chemotaxis using model system Dictyostlium discoideum using state-of-art imaging technology to systematically monitoring GPCR mediated signaling pathways at National Institute of Allergy and Infectious Diseases. In 2006, shewas recruited to Georgetown University School of Medicine as the director of Dynamic Imaging in Microscope Imaging Shared Resources. Xu further expanded her research to understand macrophage chemotaxis in metastasis of breast cancer cell and also human neutrophil chemotaxis. She has published more than 30 papers in reputed journals and serves as an editorial board member of several journals and grant review committee.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords