alexa Molecular Approach To Optimal Choice Of Specific Immunotherapy Of Patients With Sensitization To Weed Pollen Allergens
ISSN: 2155-6121

Journal of Allergy & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Share This Page

Additional Info

Loading
Loading Please wait..
 

11th International Conference on ALLERGY, ASTHMA & CLINICAL IMMUNOLOGY
September 07-08, 2017 | Edinburgh, Scotland

Zubchenko S and Danylo Halytsky
Danylo Halytsky Lviv National Medical University, Ukraine
Posters & Accepted Abstracts: J Allergy Ther
DOI: 10.4172/2155-6121-C1-006
Abstract
Introduction: The problem of pollen allergy including pollen of weeds is important for the population of Western Ukraine, including Lviv region. Aim: Aim of this study is to compare possibility of SPT and component diagnostics to select appropriate specific immunotherapy. Materials & Methods: 48 patients of both the sexes, aged 18-65 years, residents of Lviv region with seasonal allergic rhinitis/ conjunctivitis, were selected according to primary stay in the first week of August this year. SPT performed to extract pollen allergens from local sources including a mixture of weeds, grasses and extracts of ambrosia, ragweed and timothy. ImmunoCAP was used for molecular researches of sIgE. Results: In 50% of patients, positive SPT was found to mixture of weed, extracts of ambrosia, ragweed and grass mixtures. This indicated co-sensitization to various sources of allergens. 30% of patients had mono-sensitization to weeds pollen, and 20% mono-sensitization to grass pollen. However, simultaneous sensitization to pollen of ambrosia, ragweed and timothy has not been proven by molecular researches. Instead, 20% of patients identified sensitization to ragweed and ambrosia, 30% of people identified mono-sensitization to ambrosia and 20% mono-sensitization to ragweed. Most (70%) of patients with mono-sensitization to pollen of weeds identified specific IgE to Art v1 and/or Art v3, and/or Amb a1. False positive results of SPT indicated that co-sensitization to grasses and weeds can be explained by the presence of sIgE for cross-reactive markers of profilin Phl p 12 and polcalcin-Phl p 7. Conclusion: On the basis of SPT and molecular researches, doctor takes a fundamentally different decision on the selection of extracts for specific allergen immunotherapy. Optimal allergic immunotherapy is based on the identification of primary sensitizer and cross-reactivity markers.
Biography

Zubchenko S is pursuing her PhD in Medical Sciences and is an Assistant Professor at Danylo Halytsky Lviv National Medical University in Department of Clinical Immunology and Allergology. She is a Clinical Immunologist and Allergologist. She was a participant of numerous congresses, conferences, training courses, which are organized by EAACI.

image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords