alexa Therapeutics From Insects | 13720
ISSN: 2161-1009

Biochemistry & Analytical Biochemistry
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

International Conference and Exhibition on Biochemical & Molecular Engineering
October 07-08, 2013 Hilton San Antonio Airport, TX, USA

AlaaEddeen Seufi Mohamed
ScientificTracks Abstracts: Biochem Anal Biochem
DOI: 10.4172/2161-1009.S1.002
Abstract
Many have been published on therapeutic derivatives from living organisms including insects. More than 900 therapeutic products were isolated from insects. Most people think in insects as enemies but my thought is that insects are our friends not our enemies as those see. Many beneficial insects other than honey bees, silk worms and shellac insect can be seen. Insects could be our MicroFactories, Biosensors or Bioreactors. InsectFarm is an amazing example of the applied research that transfers the insects from laboratory to market. Prof Dr Mircea Ciuhrii (The founder of InsecFarm) is Italian Entomologist who worked for 18 years to derive therapeutics from insects. He derived more than 30 commercial medicines from insects (Imunomax, Noblesse, etc.). Many approaches were followed in this respect. Many laboratories took the biochemical approach to purify components of the innate immune system of insects and insect metabolites to be used in many therapeutic purposes. Others took the molecular proteomic approach to sequence and/ or synthesize components of the innate immune system of insects and to use these components in medicine. The Approach of Our Laboratory is different somehow. We used different routes of administration to induce the insect immune system, then a transcriptomic study was done to discover the induced genes and to identify specific biomarkers that can help in drug discovery. Biomarkers play an important role in medicine and in drug discovery and development as well. Optimum biomarker development and application will require a team approach because of the multifaceted nature of biomarker selection, validation, and application. This team use techniques such as pharmacoepidemiology, pharmacogenetics, pharmacogenomics, and functional proteomics; bioanalytical development and validation; disease process and therapeutic intervention assessments; and pharmacokinetic/ pharmacodynamic modeling and simulation to improve and refine drug development. The team approach will minimize the effect of such component on the rest of the process. Our Achievements included the discovery of three components of the innate immune system of the cotton leafworm, Spodoptera littoralis . These components were designated as Spli Def (defesin), Spli Lec (lectin) and Spli Cec (cecropin). Spli Def and Spli Lec were confirmed as antimicrobial peptides, while Spli Cec was additionally confirmed as anticancer peptide. Our current research is going on to achieve something in antioxidants and anticoagulants from insects. Our perspective is to achieve something in the mass production of prototypes of our products and to reach it to the commercial level. These achievements are the integrated contributions of everybody in my team staff.
image PDF   |   image HTML
 

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

clinic[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version