alexa Abstract | Effect of Aging on the Blowout Time in Various Ocular Vessels
ISSN: 2329-8847

Journal of Aging Science
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


The blowout time (BOT) is an index for assessing vascular function based on pulse wave analysis using laser speckle flowgraphy (LSFG). The BOT in the optic nerve head (ONH) is reportedly correlated with age. The ONH contains various vessels with differing properties, and it is unclear whether aging affects these vessels at similar rates. With the aim of using the BOT for the early detection of vascular changes, this study investigated whether there are regional differences in the effect of aging on the BOTs among the vessel area (MV), tissue area (MT), and all areas (MA) of the entire ONH, retinal artery (RA), retinal and choroidal vessels (RCV), and retinal vein (RV). We measured the ocular blood flow velocity for 6 s in 14 young and 14 middle-aged males (20 ± 2 years and 51 ± 10 years) three times using LSFG. The BOTs in the MV, MT, MA, RA, RCV, and RV were determined separately as the full width at half maximum of the mean blue rate in a heartbeat by pulse wave analysis. The BOTs in all of the targeted areas were significantly smaller in the middle-aged group than the young group and were significantly correlated with age. There was no significant interaction of age and differences in area. There were significant correlations in the BOTs between the MA and other targeted areas. It is suggested that the BOT in the entire ONH reflects the age-related changes in BOTs over a wide range of ocular vessels.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Miyaji A, Ikemura T and Hayashi N


Blowout time, Age, Optic nerve head, Retinal vessels, Choroidal vessels, Age, Aging

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version