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Research Article Open Access
Background: Adverse drug events (ADEs) are a major health and economic problem. There is no information regarding incidence of ADEs in Cabo Verde and trigger tools are an efficient active data collection method.
Objective: To identify efficacy of the trigger tool in identification of suspected ADRs.
Method: The Global Trigger Tool (GTT) developed by the Institute for Healthcare Improvement (IHI) was used for a retrospective review of medical records. The ADE trigger tool included 21 triggers. 383 records were randomly selected, 190 in a first period and 194 in second period. Hospitalization for less than 48h, time spent in intensive care unit and lack of drug administration records was excluded.
Results: 287 triggers and 182 ADEs were found. Medical records with at least one trigger were 67.7% and 42.7%, respectively. In the same periods, 28.4% and 19.6% of total patients presented at least one ADE but it was 50% and 67.9% when calculating for the records with a trigger. In both periods, most common and robust trigger was nurse description. The least robust were abrupt medication stop and use of antiemetic drug.
Conclusion: The trigger tool had a good performance detecting ADE. The GTT is not feasible as routine PV method but an option to complement spontaneous notification. Further studies are needed using prospective method and extended period.
Pharmacovigilance, Cape Verde, Safety monitoring, Adverse drug event monitoring, Trigger tool, Hospital pharmacovigilance, Efficacy of trigger tool, Medication Error