alexa Abstract | The Effect of Plaque Removal on Pressure Drop and Flow Rate through an Idealized Stenotic Lesion
ISSN: 0974-8369

Biology and Medicine
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article Open Access


Numerical calculations have been performed to quantify the importance of plaque removal on blood flow. The artery under consideration is the popliteal artery which is susceptible to plaque lesions. An orbital artherectomy device was used to partially remove a calcified plaque layer. Measurements taken before and after the treatment were used in idealized calculations and pressure losses through the lesion were determined. It was found that the removal of plaque by orbital atherectomy increases the blood flowrate through the artery. At the same time, there is a major reduction of pressure loss through the lesion. After treatment, the systolic pressure drop was 2.5 times less than prior to treatment. The cycle-averaged pressure drop was improved by a factor of 3.5. The results are similar for a wide range of plaque lesion lengths (from 3 mm to 18 mm). A deeper investigation into the source of pressure loss reveals that the majority of the loss is confined to the entrance of the lesion and is caused by flow acceleration (and later deceleration) rather than by friction. The calculations were repeated with three increasingly complex numerical methods (steady laminar, unsteady laminar, and unsteady transitional). It was found that all methods were in good agreement so that more computationally expensive techniques are not required in order to obtain accurate results. The results of the simulation were compared with clinical pressure measurements before and after treatment. The two results were found to be in good agreement.

To read the full article Peer-reviewed Article PDF image | Peer-reviewed Full Article image

Author(s): Brian D. Plourde, Lauren J. Vallez, Biyuan Sun, John P. Abraham and Cezar S. Staniloe


Cardiovascular disease, Plaque, Blood flow, Stenosis, Computational fluid dynamics, Biomedical Engineering

Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version