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Journal of Blood Disorders & Transfusion

ISSN: 2155-9864

Journal of Blood Disorders & Transfusion

Autoimmune Haemolytic Anaemia

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Autoimmune Haemolytic Anaemia

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Autoimmune hemolytic anemia is a group of disorders characterized by a malfunction of the immune system that produces autoantibodies, which attack red blood cells as if they were substances foreign to the body. Autoimmune hemolytic anemia is an uncommon group of disorders that can occur at any age. These disorders affect women more often than men. Autoimmune hemolytic anemia can also be caused by or occur with another disorder, such as systemic lupus erythematosus (lupus), and rarely it follows the use of certain drugs, such as penicillin.

Autoimmune hemolytic anemia (AIHA) is caused by autoantibody-induced hemolysis usually idiopathic and is also associated with infection, lymphoproliferative disorders, autoimmune diseases, and some drugs. Autoimmune hemolytic anemia is of two type’s warm and cold diseases called warm autoimmune hemolytic anemia and chronic cold agglutinin disease. Paroxysmal cold hemoglobinuria (PCH) is rare disease induced most often by postviral Donath-Landsteiner autoantibody at cold temperatures in children. Treatment of Autoimmune Haemolytic Anaemia is usually a steroid medication, such as prednisone. If steroid medications do not improve the condition, treatment with intravenous immunoglobulin (IVIG) or removal of the spleen (splenectomy) may be considered.

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 Anaemia journals, Thrombosis journals, Lupus journals

Autoimmune Haemolytic Anaemia

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