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Volume 4, Issue 5(Suppl) J Infect Dis Ther
ISSN: 2332-0877 JIDT, an open access journal
Page 44
Euro Infectious Diseases 2016
September 05-06, 2016
conferenceseries.com
Infectious Diseases
September 05-06, 2016 Frankfurt, Germany
3rd Euro-Global Conference on
Surveillance systems for nosocomial infections: Principles and challenges
Manoochehr Karami
Hamadan University of Medical Sciences, Iran
Nosocomial Infections (NIs) are considered to be serious public health problems around the world. The NI-related burden
is unknown because of lack of access to reliable data, lack of surveillance systems and the complexity of corresponding NI
outcomes. Health care systems use different approaches for monitoring NIs. Generally, surveillance methods are categorized under
the umbrellas of active, passive and sentinel surveillance methods. At present, hospitals implement passive surveillance approaches
because of feasibility and low cost. However, the quality of this methodology is in question; under reporting and lack of timeliness
are the main challenges. In contrast to the passive approach of NI surveillance systems, active ones do not face the challenge of real-
time detection of hospital-acquired infection and provide high quality data on the trends and burdens of NIs. This approach needs
extensive resources. Lessons learnt from the implementation of passive approaches to NI surveillance, especially in low and middle
income countries, have revealed the necessity of implementation of integrated sentinel surveillance methods using active approaches
at selected hospitals/health care facilities. Selecting representative hospitals can contribute to an appropriate understanding of NI-
related burden.
J Infect Dis Ther 2016, 4:5(Suppl)
A study of antibiotic susceptibility of clinical strains of Pseudomonas aeruginosa in University Hospital
Center in Batna, Algeria
Merradi Manel1, Ayachi Ammar2 and Kassah Laouar Ahmed3
1Batna 2 University, Algeria
2Batna 1 University, Algeria
3Biology Central Laboratory CAC Batna, Algeria
Pseudomonas aeruginosa is an important opportunistic pathogen that plays an important role in hospital and causes a wide
spectrum of nosocomial infections that can lead to sepsis, pneumonia, endocarditis and urinary tract infections. The development
of resistance of P. aeruginosa to antibiotics is increasing globally due to the overuse of antibiotics. This study examines the antibiotic
resistance in clinical isolates of P. aeruginosa that was carried out in the Central Bacteriology Laboratory, University Hospital Center
in Batna from January 2015 to December 2015. All samples received in the laboratory were processed according to Clinical and
Laboratory Standards Institute (CLSI, 2014) guidelines. Identification of P. aeruginosa was done by conventional (Api 20 NE)
techniques and antimicrobial susceptibility pattern to 14 antimicrobial agents was determined by disc diffusion method and total of
199 patients with mean age of 24.15±22.15 (50.25% males and 49.75% females). The resistance was seen with Levofloxacin 21.6%,
Ceftazidime 9.55%, Piperacillin 38.68%, Colistin 6.03%, Gentamicin 30.15%, Ciprofloxacin 9.04% Aztreonam 8.54% and Imipenem
was 14.07%. The most frequent mechanisms of resistance were OprD2 (2.01%) and metallo-b-lactamase MβL (1%). The most affected
departments were: Burned (29.14%), Neurosurgery (17.58%) and the Medical-ICU (11.55%). Specimens’ frequency according to the
isolation rate was: Pus (53.77%) and cerebrospinal fluid (12.56%). In the present study Aztreonam, Ceftazidime, Ciprofloxacin and
Colistin were found to be the most effective drugs against P. aeruginosa.