Journal of Blood Disorders & Transfusion

David Seaton

Publications

• Research Article
  Application of Massive Transfusion Protocol is Associated with a Low Incidence of Coagulopathy and Mortality Rate
  Author(s): Alhossain Khalafallah, Abdul-Majeed Albarzan, Amit Ganguly, Gerald Bates, Fiona Gavin, Kiran DK Ahuja, David Seaton and Terry BrainAlhossain Khalafallah, Abdul-Majeed Albarzan, Amit Ganguly, Gerald Bates, Fiona Gavin, Kiran DK Ahuja, David Seaton and Terry Brain
  
  Background: Massive haemorrhage and subsequent Massive Transfusion (MT) are associated with serious, often fatal complications including intractable Disseminated Intravascular Coagulation (DIC). Historically undesirable outcomes demonstrate the need to improve the management approach of MT. It is clear that evidence-based guidelines and protocols should be developed with the aim of improving MT-outcome. Methods: We implemented an evidence-based MT-Protocol (MTP) in 2007 and studied all patients (105) from Jan 2008 to Jan 2011 who required MT and were treated with the MTP at our institution. The MTP includes two phases and incorporates a fixed volume of Fresh Frozen Plasma (FFP), cryoprecipitate and platelets in addition to Packed Red Blood Cells (PRBC). Results: The median age of patients was 57 years (range, 18-86.. View More»
  DOI: 10.4172/2155-9864.1000123

  Abstract PDF