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De Oliveira GC
De Oliveira GC
Brazil
Publications
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Research Article
Stimulated And Non-Stimulated Salivary Flows Should Be Tested For The Presence Of HCV RNA In Saliva Samples From Patients With Chronic Hepatitis C
Author(s): Grossmann SMC, De Oliveira GC, Teixeira R and Vieira do Carmo MAGrossmann SMC, De Oliveira GC, Teixeira R and Vieira do Carmo MA
Objective: In most of the studies which analyzed the presence of HCV RNA in saliva from patients with chronic hepatitis C only stimulated saliva samples have been used for viral detection. Thus, this study compared the prevalence of HCV RNA in non-stimulated and stimulated salivary flows in patients with chronic hepatitis C. Design: Saliva samples of non-stimulated and stimulated salivary flows from 24 patients were collected, and the HCV RNA was investigated by RT-nested PCR. Data regarding age, gender, risk factors for HCV infection, xerostomia and hyposalivation were also analyzed. Results: The HCV RNA could be detected in 11 (45.8%) non stimulated and in 14 (58.3%) stimulated saliva samples, without statistical significance (p=0.472). However, in 18 (75.0%) patients it was possible t.. View More»
DOI: 10.4172/2161-1122.1000232