Journal of Stem Cell Research & Therapy

Dina Sabry

Publications

• Research Article
  The Possible Ameliorative Effect of Mesenchymal Stem Cells and Curcumin Onbleomycin Induced Lung Injuries in the Adult Male Rats: Histological and Immunohistochemical Study
  Author(s): Zeinab MAltaib, Aisha EMansy, Abeer M ElMahlawy and Dina SabryZeinab MAltaib, Aisha EMansy, Abeer M ElMahlawy and Dina Sabry
  
  Background: Bleomycin (BLM) is a chemotherapeutic agent that produces pulmonary fibrosis. Curcumin is a naturally occurring compound, uses in medicine and has many beneficial therapeutic effects. Bone Marrow Mesenchymal Stem Cells (BMSCs) is a novel approach with great therapeutic potential for the treatment of fatal pulmonary fibrosis. Aim of the work: To evaluate whether or not curcumin improves the stem cells therapeutic effects on bleomycin induced lung injuries in adult male rats. Material and methods: Fifty adult male rats were included and divided equally into 5 groups. Group I (control), Group II (bleomycin group): The rats received single intratracheal instillation of 1 mg/kg of bleomycin, Group III (curcumin group): The rats received curcumin 200 mg/kg body weight orally by gastric tube 5 days/week for 4 weeks, Group IV (stem cell group): The rats injected intraperitoneal by.. View More»
  DOI: 10.4172/2157-7633.1000389

  Abstract PDF