Dentistry

Gregory T MacLennan

Publications

• Research Article
  Periodontal Treatment Improves Prostate Symptoms and Lowers Serum PSA in Men with High PSA and Chronic Periodontitis
  Author(s): Naif Alwithanani, Nabil F Bissada, Nishant Joshi, Donald Bodner, Catherine Demko, Gregory T MacLennan, Robert Skillicorn, Lee Ponsky and Sanjay GuptaNaif Alwithanani, Nabil F Bissada, Nishant Joshi, Donald Bodner, Catherine Demko, Gregory T MacLennan, Robert Skillicorn, Lee Ponsky and Sanjay Gupta
  
  Objective: To assess changes in voiding symptoms, serum PSA and inflammatory cytokine levels after non-surgical periodontal treatment in men with chronic periodontitis. Patients and methods: Twenty-seven men who underwent prostate biopsy because of abnormal findings on digital rectal examination or elevated PSA (≥4 ng/ml) participated in the study. Dental plaque (PI) and gingival(GI) indices, bleeding on probing (BOP), probing depth (PD), clinical attachment level (CAL), gingival recession(GR), PSA, IPSS, IL-1β, and C-Reactive Protein (CRP) were determined before and after periodontal treatment. The Mann-Whitney test was used to compare PSA level at baseline with prostate inflammation, prostate malignancy, and Gleason score. The Wilcoxon Rank-Sum Test was used to exa.. View More»
  DOI: 10.4172/2161-1122.1000284

  Abstract PDF