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Junxi Xiang
Junxi Xiang
China
Publications
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Research Article
Effect of Static Magnetic Fields on Proliferation and Apoptosis of Gallbladder Cancer Cells: An in vitro and in vivo study
Author(s): Huan Yang, Junxi Xiang, Jian Dong, Jiwen Cheng, Xinglong Zheng, Peng Liu, Rongqian Wu and Yi LvHuan Yang, Junxi Xiang, Jian Dong, Jiwen Cheng, Xinglong Zheng, Peng Liu, Rongqian Wu and Yi Lv
Objectives: The knowledge on how static magnetic fields (SMF) of magnetic implants affect living cells and tissues is limited while these magnetic devices are more and more frequently adopted in certain surgical approaches. Methods: In this study, we exposed cultures of human gallbladder cancer cells to SMF continuously for up to 7 days, trying to simulate the exposure pattern of surgical magnetic implants, and implanted magnetic devices into tumor-bearing nude mice for 1 month, then evaluated the effect on proliferation and apoptosis of cancer cells and tissues. Results: It showed that after SMF exposure, whereas in vitro study showed decreased cell proliferation and increased apoptosis of the gallbladder cancer cells, in vivo study showed no significant differences both on proliferation and on apoptosis. .. View More»