Journal of Liver

Nazila Vahidi-eyrisofla

Publications

• Research Article
  The Study of Levofloxacin Effects on Liver Tissue in Wistar Rat
  Author(s): Nazila Vahidi-eyrisofla, Mehdi Ahmadifar, Ali-Mohammad Eini and Arsalan KalamiNazila Vahidi-eyrisofla, Mehdi Ahmadifar, Ali-Mohammad Eini and Arsalan Kalami
  
  Introduction and objective: In this study, we examined the effects of the antibiotics levofloxacin on the liver as well as its devastating effects which are ensued from its over-prescription. Levofloxacin serves as one of the antibiotics of genitourinary system and inferior respiratory system. Since liver is the foremost organ that receives all the materials absorbed by intestine through the portal vein, and it is the organ that must neutralize venoms, the toxic effect of most medications on liver manifest itself quicker than other organs. Methodology: For this study, the experiment used 50 male Wistar rats each weighing approximately 250 ± 15 g. Experiments were conducted. In the first experiment, G1-control, G2-control sham, G3-control plus 0.03 mg/kg, G4- control plus 0.06 mg/kg, G5-control plus 0.08 mg/kg for a 60 days experimental period. The drug was administered orally o.. View More»
  DOI: 10.4172/2167-0889.1000173

  Abstract PDF